BCMA-Luc K562
CBP74667
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| I. Background | |
| BCMA（B细胞成熟抗原）是TNF受体超家族成员，由TNFRSF17基因编码，主要表达于浆细胞和成熟B细胞表面。它在多发性骨髓瘤细胞上高表达，是浆细胞存活的关键分子，也是CAR-T、双特异性抗体和ADC等抗骨髓瘤疗法最重要的靶点之一。 | |
| II. Description | |
| BCMA-Luc K562 细胞，在K562细胞的基础上，稳定表达 BCMA-Luc。 | |
| III. Introduction | |
| Expressed gene: | BCMA-Luc |
| Host Cell: | K562 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640 +10%FBS +5μg/ml Blasticidin +1 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant BCMA-Luc K562 constitutively expressing BCMA-Luc. |
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