IL17RA HEK293
CBP74660
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| I. Background | |
| IL17RA(白细胞介素-17受体A)由IL17RA基因编码,是IL-17受体家族中最重要的共用信号传导亚基。它是IL-17A、IL-17F、IL-17C、IL-17E(IL-25)等多种细胞因子的受体复合物的共同组成部分,顺利获得招募ACT1等衔接蛋白激活NF-κB和MAPK通路,在炎症反应、中性粒细胞募集和宿主防御中发挥核心作用。该基因缺陷可导致家族性念珠菌病5型,表现为对念珠菌的易感性增加。 | |
| II. Description | |
| IL17RA HEK293细胞,在 HEK293细胞的基础上,稳定表达 IL17RA。 | |
| III. Introduction | |
| Expressed gene: | IL17RA |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
Figure 1. Recombinant IL17RA HEK293 constitutively expressing IL17RA. |
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