Cyno TFRC CHO
CBP74657
询 价
索取Protocol
产品描述
产品数据库
| I. Background | |
| 食蟹猴(Cynomolgus monkey)的 TFRC 基因编码转铁蛋白受体蛋白 1(Transferrin receptor protein 1),是细胞摄取铁的核心受体,顺利获得受体介导的内吞作用将结合了铁的转铁蛋白转运入细胞,对红细胞生成和神经系统发育至关重要。在生物医药领域,TFRC(CD71)也是血脑屏障上介导受体介导转胞吞作用(RMT)的关键靶点,常用于评估大分子药物入脑递送能力。 | |
| II. Description | |
| Cyno TFRC CHO细胞,在 CHO-K1 细胞的基础上,稳定表达 Cyno TFRC。 | |
| III. Introduction | |
| Expressed gene: | Cyno TFRC |
| Host Cell: | CHO-K1 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+ 600 μg/ml Hygromycin B |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
Figure 1. Recombinant Cyno TFRC CHO constitutively expressing Cyno TFRC. |
|